Despite significant obstacles that have delayed the establishment of the Weapons of Mass Destruction (WMD)-Free Zone in the Middle East, it remains the only multilateral and comprehensive effort to address the threat of WMD in the region. The need for such a zone has only grown over recent years as WMD-related threats in the region have increased in complexity and as regional security dynamics have become more volatile than ever before. This report summarizes the main activities of UNIDIR’s Middle East WMD-Free Zone Project between 2023 and 2026 and highlights key takeaways from the project’s observation of political processes, research and dialogue.