The Non-Proliferation Treaty (NPT) commemorates its fiftieth anniversary in force at a time when the Doomsday Clock has been set to 100 seconds. The nuclear arms control architecture has been undermined and an environment is being created for a renewed nuclear arms race. What is needed is for diplomats to find the required political compromises to build on common ground. Only through this cooperation can we strengthen the authority and integrity of the NPT and re-engage constructive progress toward nuclear disarmament and risk reduction.